Rodent Genetic Engineering Laboratory

Covid update

All researchers visiting the Core must wear masks and maintain social distancing when possible. 

TERMS AND CONDITIONS:

By placing this order in iLab, user agrees to and accepts the Terms and Conditions governing the provision of shared core biomedical research services (“Services”) by NYU Grossman School of Medicine (“NYU”).

The Services are provided by NYU on an "AS IS" and "AS AVAILABLE" basis and without any express or implied warranties.

Overview of Services

NYU Grossman School of Medicine’s Rodent Genetic Engineering Laboratory (RGEL) is a resource for researchers who want to apply advanced molecular genetic techniques in rodent models of physiology and disease. Our lab is experienced at generating novel mutant mouse strains by using gene targeting in embryonic stem cells (ESCs) and by developing novel methods of modifying rodent genomes and assaying genetically modified cells in vivo. Our lab scientists customize technologies to meet individual project needs, including specialized expertise in the use the clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) systems and other approaches for direct genome editing in vivo. Available advanced technologies include CRISPR/Cas9, a proprietary rapid strain-creation method known as the EZ-Mouse Model (tetraploid complementation systems), GEMMs-ESC Speedy cancer animal models, regulated gene expression by high-throughput RNA interference assay in mice (RNAi mice), safe-harbor knock-in gene editing using the Rosa26 and other loci, recombinase-mediated cassette exchange, Inducible Tet-On® and Tet-Off® Gene Expression Systems, homologous recombination, induced pluripotent stem cells, assisted reproductive technologies, and vitrification systems.

Leadership

Sang Yong Kim,Ph.D
Director
Phone: 646-501-0605
Email: Sang.kim@nyulangone.org

Ran Broh,Ph.D
Associate Director
Email: ran.brosh@nyulangone.org 

Location and hours of operation

Links and Resources

1. www.Ensembl.org
2. www.genome.ucsc.edu
3. www.NCBI.nlm.nlh.gov
4. Crispr.mit.edu
5. Rodent Genetic Engineering Laboratory

Contacts